CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12365
Family Name Coagulation factor X and Prothrombin inhibitor SureCN8237487 family
No. of Seeds 16 No. of Other Members 1
Family Centroid CFAMM00330836 Functional Category Bioactive
Superfamily Prothrombin and Coagulation factor X Binder Superfamily 4
Class Class 913

Cousin Family NamesSeedsMembers
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Growth hormone receptor Ligand EP-51216 Family 34 390
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Cycl... 7 6
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(6-aminopyr... 1 4
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-073U... 3 8
Neuropeptide Y receptor type 5 ligand 2-(6-chloroindol-1-yl)-N... 4 23
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Coagulation factor X inhibitor SureCN4172349 family 7 3
Coagulation factor X inhibitor (6S,8aS)-N-[(6-amino-2-methylpy... 1 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Prothrombin and Tissue-type plasminogen activator inhibitor 2-... 4 5
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
Coagulation factor X and Prothrombin inhibitor SureCN8243313 f... 10 8
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
KiSS-1 receptor ligand SureCN5132924 family 2 4


External ID

Functional Category

Molecule Name

CFAMM00415230 CHEMBL230981 Bioactive (2R)-2-(benzylsulfonylamino)-N-[2-[(3-chlorophenyl)methylamino]-2-oxoethyl]-4-(1-oxidopyridin-1-ium-2-yl)butanamide
CFAMM00415236 CHEMBL231292 Bioactive AGN-PC-00SAU0
CFAMM00415228 CHEMBL397895 Bioactive (4S)-5-[[2-(aminomethyl)-5-chlorophenyl]methylamino]-4-[[(2R)-2-(benzylsulfonylamino)-4-(1-oxidopyridin-1-ium-2-yl)butanoyl]-methoxyamino]-5-oxopentanoic acid
CFAMM00415227 CHEMBL231494 Bioactive SureCN8242816
CFAMM00415234 CHEMBL397679 Bioactive AGN-PC-0766DL
CFAMM00415237 CHEMBL442228 Bioactive SureCN10020328
CFAMM00415233 CHEMBL389960 Bioactive SureCN8244943
CFAMM00415232 CHEMBL228612 Bioactive SureCN8241457
CFAMM00415231 CHEMBL396286 Bioactive SureCN8241453

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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