CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12366
Family Name RAC-beta serine/threonine-protein kinase inhibitor SureCN5728390 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00415239 Functional Category Bioactive
Superfamily RAC-beta serine/threonine-protein kinase and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 1941

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
XL-888 family 16 85
Tyrosine-protein phosphatase non-receptor type 1 Ligand 6-(oxa... 1 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 3 4
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
Survival motor neuron protein and Menin inhibitor CHEMBL130937... 1 7
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 1 1
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Cyclin-dependent kinase 2 and Vascular endothelial growth fact... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415239 CHEMBL228648 Bioactive SureCN5728390
CFAMM00415238 CHEMBL228649 Bioactive SureCN5728305

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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