CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12368
Family Name Integrin alpha-4 inhibitor SureCN14558471 family
No. of Seeds 16 No. of Other Members 2
Family Centroid CFAMM00415254 Functional Category Bioactive
Superfamily Integrin alpha-4 and Menin Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Liga... 17 31
Integrin beta-1 and Integrin alpha-4 inhibitor AGN-PC-02YIN5 f... 3 5
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 18 2
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 1 3
Prostaglandin D2 receptor 2 ligand AGN-PC-07CQC5 family 4 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415265 CHEMBL515819 Bioactive 4-[[(2S,4S)-1-[2-[4-[(2-bromophenyl)carbamoylamino]-5-chloro-2-fluorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415250 CHEMBL456399 Bioactive 4-[[(2S,4S)-1-[2-[2,5-dichloro-4-[(2-chlorophenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415256 CHEMBL457223 Bioactive 4-[[(2S,4S)-1-[2-[3-chloro-4-[(5-fluoro-2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415264 CHEMBL456180 Bioactive 4-[[(2S,4S)-1-[2-[5-chloro-4-[(2-chlorophenyl)carbamoylamino]-2-fluorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415255 CHEMBL456608 Bioactive 4-[[(2S,4S)-1-[2-[5-chloro-4-[(2-chlorophenyl)carbamoylamino]-2-methylphenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415263 CHEMBL387660 Bioactive SureCN14558467
CFAMM00415254 CHEMBL387659 Bioactive SureCN14558471
CFAMM00415262 CHEMBL390057 Bioactive SureCN14558385
CFAMM00415253 CHEMBL456814 Bioactive 4-[[(2S,4S)-1-[2-[2,5-dichloro-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415267 CHEMBL425647 Bioactive SureCN14558466
CFAMM00415252 CHEMBL456815 Bioactive 4-[[(2S,4S)-1-[2-[5-chloro-2-fluoro-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415260 CHEMBL515662 Bioactive 4-[[(2S,4S)-1-[2-[5-chloro-2-methyl-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415258 CHEMBL456347 Bioactive 4-[[(2S,4S)-1-[2-[4-[(2-bromophenyl)carbamoylamino]-2,5-dichlorophenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415266 CHEMBL515348 Bioactive 4-[[(2S,4S)-1-[2-[3-chloro-4-[(4-fluoro-2-methylphenyl)carbamoylamino]phenyl]acetyl]-4-fluoropyrrolidin-2-yl]methoxy]benzoic acid
CFAMM00415259 CHEMBL228730 Bioactive SureCN14558476
CFAMM00415257 CHEMBL456348 Bioactive SureCN14558491

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45925 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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