CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12369
Family Name Prothrombin and Coagulation factor X inhibitor [(1R)-5-amino-1-[[2-[methyl-(2-phenylsulfanylbenzoyl)amino]acetyl]amino]pentyl]boronic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00251671 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Prothrombin Binder Superfamily
Class Class 2613

Cousin Family NamesSeedsMembers
DNA Binder Procarbazine Family 8 358
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Neutrophil elastase Inhibitor FK-706 Family 8 85
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Cathepsin S and Cathepsin K inhibitor N-[(2R)-1-[[cyano(methyl... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Prolyl endopeptidase and Seprase inhibitor [(2R)-1-[2-[benzoyl... 2 0
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Retinal dehydrogenase 1 and 15-hydroxyprostaglandin dehydrogen... 2 0
Coagulation factor X and Prothrombin inhibitor N-[2-[[(3S)-7-a... 1 1
NP Methyl 5-((2s,3s,4r)-4-benzamido-3-chlorotetrahydrothiophen... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415269 CHEMBL282281 Bioactive [(1R)-5-amino-1-[[2-[[2-(2-cyanophenyl)sulfanylbenzoyl]-methylamino]acetyl]amino]pentyl]boronic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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