CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12385
Family Name Beta-secretase 1 inhibitor N-[(2S,3R)-3-amino-4-fluoro-1-phenylbutan-2-yl]-2-[[(1S,2S)-2-methylcyclopropyl]methylamino]-6-[methyl(propan-2-ylsulfonyl)amino]pyridine-4-carboxamide family
No. of Seeds 4 No. of Other Members 17
Family Centroid CFAMM00415427 Functional Category Bioactive
Superfamily Trypsin-1 and Prothrombin Binder Superfamily 8
Class Class 122

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Coagulation factor X inhibitor (6S,8aS)-N-[(6-amino-2-methylpy... 1 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 0
Transient receptor potential cation channel subfamily V member... 57 4
Transient receptor potential cation channel subfamily V member... 2 0
Prothrombin and Trypsin-1 inhibitor AGN-PC-073JJH family 5 7
Prothrombin and Trypsin-1 inhibitor N-[(6-amino-2-methylpyridi... 3 0
Prothrombin and Trypsin-1 inhibitor AGN-PC-073QCQ family 3 0


External ID

Functional Category

Molecule Name

CFAMM00415427 CHEMBL230245 Bioactive N-[(2S,3R)-3-amino-4-fluoro-1-phenylbutan-2-yl]-2-[[(1S,2S)-2-methylcyclopropyl]methylamino]-6-[methyl(propan-2-ylsulfonyl)amino]pyridine-4-carboxamide
CFAMM00415407 CHEMBL247043 Bioactive SureCN13817964
CFAMM00415412 CHEMBL247416 Bioactive SureCN13818090
CFAMM00415422 CHEMBL429477 Bioactive isonicotinamide, 27

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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