CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12389
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-PC-0766FM family
No. of Seeds 8 No. of Other Members 6
Family Centroid CFAMM00415471 Functional Category Bioactive
Superfamily Histone deacetylase 6 and Histone deacetylase 1 Binder Superfamily
Class Class 1555

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Rimonabant Family 20 260
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Reverse transcriptase Inhibitor IDX899 Family 2 118
D(3) dopamine receptor Ligand SB-277011 Family 13 178
D(4) dopamine receptor Ligand SPI-376 Family 7 84
Cannabinoid receptor 1 Ligand TM38837 Family 20 15
Setipiprant family 5 118
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand [2... 2 5
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 1 10
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 13
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Cellular tumor antigen p53 and Ferritin light chain inhibitor ... 1 2
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SVV family 2 12
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL186461 family 2 4
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 2-... 3 0
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Translocator protein inhibitor N-(4-chlorophenyl)-N-methyl-2-(... 2 0
Translocator protein inhibitor N,N-diethyl-11-(2-fluoroethyl)-... 14 9
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
Cannabinoid receptor 1 ligand SureCN4819820 family 11 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Coagulation factor X inhibitor SureCN8169809 family 12 18
Substance-P receptor ligand SureCN7796965 family 9 1
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Prostaglandin D2 receptor 2 ligand 2-[3-[(3-chlorophenyl)-meth... 1 0
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Motilin receptor ligand SureCN2768052 family 3 0
Acetylcholinesterase inhibitor N-[6-[4-[(6-chloro-1,2,3,4-tetr... 9 0
C-C chemokine receptor type 5 ligand 6-chloro-N-[(3R)-3-[4-[(5... 16 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 17 0
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Cannabinoid receptor 1 ligand AGN-PC-07NHJ5 family 9 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Translocator protein inhibitor 2-(7-Chloro-5-methyl-4-oxo-3-ph... 1 0
Cannabinoid receptor 1 ligand AGN-PC-07R5TU family 11 0
Cannabinoid receptor 1 ligand AGN-PC-07NHI2 family 4 1
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand SureCN3822127 family 5 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
Cannabinoid receptor 1 ligand [6-bromo-2-methyl-1-(2-morpholin... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415472 CHEMBL396799 Bioactive AGN-PC-0766FQ
CFAMM00415465 CHEMBL230356 Bioactive SureCN981044
CFAMM00415471 CHEMBL396798 Bioactive AGN-PC-0766FM
CFAMM00415476 CHEMBL230992 Bioactive 1-(2-chlorophenyl)-2-(4-chlorophenyl)-5-cyclohexyl-3-methyl-6,7-dihydropyrrolo[3,2-c]pyridin-4-one
CFAMM00415469 CHEMBL230466 Bioactive AGN-PC-03JHDY
CFAMM00415475 CHEMBL231201 Bioactive 1-(2-chlorophenyl)-2-(4-chlorophenyl)-3-methyl-5-piperidin-1-yl-6,7-dihydropyrrolo[3,2-c]pyridin-4-one
CFAMM00415468 CHEMBL387782 Bioactive AGN-PC-0766FS
CFAMM00415474 CHEMBL230571 Bioactive AGN-PC-03JHE4

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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