CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12397
Family Name Melanin-concentrating hormone receptor 1 ligand 3-[4-[[3-(3-methoxyphenyl)-2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]benzonitrile family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00415510 Functional Category Bioactive
Superfamily Translocator protein and Gonadotropin-releasing hormone receptor Binder Superfamily
Class Class 2417

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
Translocator protein inhibitor CHEMBL2332259 family 2 0
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 2 6
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00415507 CHEMBL396174 Bioactive 3-[4-[[1-(cyclohexylmethyl)-3-(3-methoxyphenyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]benzonitrile
CFAMM00415510 CHEMBL230521 Bioactive 3-[4-[[3-(3-methoxyphenyl)-2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]benzonitrile

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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