CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12400
Family Name Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-[(2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)methyl]phenyl]benzonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00415520 Functional Category Bioactive
Superfamily Integrin beta-2 and Androgen receptor Binder Superfamily
Class Class 3044

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Droperidol Family 20 244
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Melanin-concentrating hormone receptor 1 ligand N-[2-[4-(3-cya... 3 9
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand SureCN13918038... 6 1
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Nociceptin receptor ligand SureCN8... 7 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloro-4-fl... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
Nociceptin receptor and Mu-type opioid receptor ligand spiropi... 1 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 7 1
Substance-P receptor ligand (2S)-2-N-[2-[(3,5-dimethylphenyl)m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415521 CHEMBL396008 Bioactive 3-[4-[[3-(3-methylphenyl)-2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]benzonitrile
CFAMM00415520 CHEMBL230627 Bioactive 3-chloro-5-[4-[(2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)methyl]phenyl]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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