CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12418
Family Name Tyrosine-protein kinase receptor TYRO3 and P-selectin ligand 2-(3,5-dichloroanilino)-4-[[(2S)-1-hydroxybutan-2-yl]amino]-N-(1-methylpiperidin-4-yl)pyrimidine-5-carboxamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00415634 Functional Category Bioactive
Superfamily Tyrosine-protein kinase receptor TYRO3 and P-selectin Binder Superfamily
Class Class 2568

Cousin Family NamesSeedsMembers
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Adenosine kinase inhibitor SureCN8320660 family 7 2
Tyrosine-protein kinase receptor TYRO3 and Mitogen-activated p... 3 7
Cannabinoid receptor 2 ligand SureCN13503317 family 7 7


External ID

Functional Category

Molecule Name

CFAMM00415634 CHEMBL2311550 Bioactive 2-(3,5-dichloroanilino)-4-[[(2S)-1-hydroxybutan-2-yl]amino]-N-(1-methylpiperidin-4-yl)pyrimidine-5-carboxamide
CFAMM00415635 CHEMBL2312652 Bioactive 2-(3,5-dichloroanilino)-4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-N-(1-methylpiperidin-4-yl)pyrimidine-5-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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