CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12435
Family Name Tyrosine-protein kinase ABL1 inhibitor AGN-PC-00AWSY family
No. of Seeds 13 No. of Other Members 3
Family Centroid CFAMM00415729 Functional Category Bioactive
Superfamily Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-protein kinase Src Binder Superfamily 2
Class Class 4538

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor beta and Ephrin type-B... 9 16
Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-00... 3 20
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 4 0
Tyrosine-protein kinase ABL1 inhibitor SureCN4264171 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00415732 CHEMBL250423 Bioactive AGN-PC-00DEJR
CFAMM00415731 CHEMBL249821 Bioactive AGN-PC-00C3FY
CFAMM00415737 CHEMBL250213 Bioactive AGN-PC-0471BN
CFAMM00415730 CHEMBL249820 Bioactive SureCN4265067
CFAMM00415736 CHEMBL250218 Bioactive AGN-PC-00CEB3
CFAMM00415729 CHEMBL250019 Bioactive AGN-PC-00AWSY
CFAMM00415742 CHEMBL250821 Bioactive AGN-PC-006GKU
CFAMM00415735 CHEMBL231220 Bioactive 4-[[(7Z)-7-(2-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)-5-methyl-1H-1,2,4-benzotriazin-3-yl]amino]-N-(2-pyrrolidin-1-ylethyl)benzenesulfonamide
CFAMM00415728 CHEMBL399268 Bioactive AGN-PC-00ENMF
CFAMM00415741 CHEMBL250021 Bioactive AGN-PC-00BYDA
CFAMM00415734 CHEMBL250625 Bioactive AGN-PC-00BSHP
CFAMM00415740 CHEMBL398845 Bioactive 4-chloro-3-[3-[4-[1-[2-(diethylamino)ethyl]piperidin-4-yl]sulfonylanilino]-5-methyl-1,2,4-benzotriazin-7-yl]phenol
CFAMM00415733 CHEMBL250623 Bioactive SureCN4269189

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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