CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12436
Family Name Muscarinic acetylcholine receptor M5 and Muscarinic acetylcholine receptor M1 ligand 2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00415743 Functional Category Bioactive with Natural Product
Superfamily D(1A) dopamine receptor and Arachidonate 5-lipoxygenase Binder Superfamily
Class Class 719

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
D(3) dopamine receptor Ligand U-99194A Family 7 33
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Acetylcholinesterase Inhibitor AP-2238 Family 2 109
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 27
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-[(4... 3 53
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 3 2
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 20
Metabotropic glutamate receptor 2 ligand 4-(3,4-dimethoxypheny... 1 0


External ID

Functional Category

Molecule Name

CFAMM00415743 CHEMBL2312346 Bioactive 2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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