CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12443
Family Name Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphenyl)sulfonyl-N-phenylpiperidine-4-carboxamide family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00415795 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Ferritin light chain Binder Superfamily
Class Class 1547

Cousin Family NamesSeedsMembers
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
72 kDa type IV collagenase Inhibitor SC-74020 Family 1 21
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
C-C chemokine receptor type 5 ligand SureCN4768594 family 5 2
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 1 0
Bifunctional epoxide hydrolase 2 inhibitor N-(2-chlorophenyl)-... 2 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 1 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor (E)-2... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 7 5
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Glucocorticoid receptor ligand SureCN3218641 family 2 7
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Prothrombin and Proteinase-activated receptor 1 ligand (2S)-N-... 2 4
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 3 2
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415798 CHEMBL2313190 Bioactive 1-(2,4-dimethylphenyl)sulfonyl-N-(2-fluorophenyl)piperidine-4-carboxamide
CFAMM00415806 CHEMBL2313175 Bioactive 1-(2,4-dimethylphenyl)sulfonyl-N-(4-propan-2-ylphenyl)piperidine-4-carboxamide
CFAMM00415797 CHEMBL2313191 Bioactive N-(2-bromophenyl)-1-(2,4-dimethylphenyl)sulfonylpiperidine-4-carboxamide
CFAMM00415795 CHEMBL2313167 Bioactive 1-(2,4-dimethylphenyl)sulfonyl-N-phenylpiperidine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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