CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12447
Family Name Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethylphenyl)sulfonylpiperidine-4-carbonyl]amino]naphthalene-2-carboxylic acid family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00415820 Functional Category Bioactive
Superfamily Genome polyprotein and Type-1B angiotensin II receptor Binder Superfamily
Class Class 4913

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Methionine aminopeptidase 2 Inhibitor 5-methyl-2-[(phenylsulfo... 7 101
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Bifunctional epoxide hydrolase 2 inhibitor methyl 4-[[1-(2,4-d... 1 2
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 18
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Methionine aminopeptidase 2 inhibitor AGN-PC-00DIXW family 3 1
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4


External ID

Functional Category

Molecule Name

CFAMM00415820 CHEMBL2313183 Bioactive 6-[[1-(2,4-dimethylphenyl)sulfonylpiperidine-4-carbonyl]amino]naphthalene-2-carboxylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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