CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12451
Family Name cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor 1-(2-chlorophenyl)-4-methyl-N-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]quinoxalin-8-amine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00186458 Functional Category Bioactive
Superfamily Tyrosine-protein kinase JAK2 Inhibitor LY2784544 Superfamily
Class Class 37

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Adenosine receptor A2b and Adenosine receptor A2a ligand CP-66... 3 33
Cellular tumor antigen p53 inhibitor CHEMBL1318500 family 1 0
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 5 1
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 2 3
Adenosine receptor A1 ligand 3-[(2-chlorophenyl)methyl]-N-cycl... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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