CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12453
Family Name Leukotriene A-4 hydrolase inhibitor 1-[1-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]piperidin-4-yl]pyrrolidin-2-one family
No. of Seeds 7 No. of Other Members 12
Family Centroid CFAMM00415846 Functional Category Bioactive
Superfamily Leukotriene A-4 hydrolase and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 1699

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase inhibitor 1-[5-[[5-([1,3]thiazolo[4,... 1 2
Leukotriene A-4 hydrolase inhibitor N-[(1S,5R)-8-[[6-(1,3-benz... 1 11


External ID

Functional Category

Molecule Name

CFAMM00415840 CHEMBL2313272 Bioactive 1-[5-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethanone
CFAMM00415848 CHEMBL2313573 Bioactive N-[(1S,5R)-8-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]-8-azabicyclo[3.2.1]octan-3-yl]acetamide
CFAMM00415847 CHEMBL2313563 Bioactive 2-[[3-(piperidin-1-ylmethyl)-1-benzofuran-6-yl]oxy]-[1,3]thiazolo[4,5-b]pyridine
CFAMM00415837 CHEMBL2313265 Bioactive 1-[(1S,4S)-5-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethanone
CFAMM00415846 CHEMBL2313571 Bioactive 1-[1-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]piperidin-4-yl]pyrrolidin-2-one
CFAMM00415843 CHEMBL2313567 Bioactive 1-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]piperidine-4-carboxylic acid
CFAMM00415853 CHEMBL2313569 Bioactive N-[1-[[6-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)-1-benzofuran-3-yl]methyl]piperidin-4-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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