CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12469
Family Name Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor SureCN937531 family
No. of Seeds 5 No. of Other Members 15
Family Centroid CFAMM00415940 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Ligand 4-(4-p-tolylamino-phthalazin-1-yl)-benzamide Superfamily
Class Class 1152

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LY2940680 Family 3 18
Smoothened homolog inhibitor SureCN1091073 family 14 22
Smoothened homolog inhibitor SureCN1090957 family 1 2
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M8RE fa... 6 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
B1 bradykinin receptor ligand SureCN6045964 family 2 1
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 7 7
Acyl-CoA desaturase and Acyl-CoA desaturase 1 inhibitor AGN-PC... 5 1
Acetylcholinesterase inhibitor 1-[3-[6-[2-(1-benzylpiperidin-4... 1 0
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor N-(1H-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00415940 CHEMBL591796 Bioactive SureCN937531
CFAMM00415944 CHEMBL2315096 Bioactive N-(4-cyclopropylbutyl)-6-[4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl]pyridazine-3-carboxamide
CFAMM00415943 CHEMBL2315095 Bioactive N-(3-cyclopropylpropyl)-6-[4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl]pyridazine-3-carboxamide
CFAMM00415936 CHEMBL2315102 Bioactive N-(4-chlorophenyl)-6-[4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl]pyridazine-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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