CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12476
Family Name Prostaglandin E synthase inhibitor 1-[5-chloro-6-(4-fluorophenyl)-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide family
No. of Seeds 8 No. of Other Members 27
Family Centroid CFAMM00416007 Functional Category Bioactive
Superfamily Integrin alpha-4 and Cathepsin S Binder Superfamily
Class Class 678

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand SB-213... 2 54
Arachidonate 5-lipoxygenase Inhibitor 5-chloro-n-phenylbenzo[d... 3 15
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Somatostatin receptor type 5 and Potassium voltage-gated chann... 2 21
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 1
Neuropeptide Y receptor type 5 ligand N-(5-chloro-1,3-benzoxaz... 1 1
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
Cathepsin S and Cathepsin L1 inhibitor SureCN5361439 family 2 4
Neuropeptide Y receptor type 5 ligand AGN-PC-07CNPD family 1 0
Somatostatin receptor type 5 ligand SureCN3572493 family 1 3
Somatostatin receptor type 5 ligand SureCN3633290 family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416011 CHEMBL2391295 Bioactive 1-(5-chloro-6-propan-2-yl-1,3-benzoxazol-2-yl)-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide
CFAMM00416024 CHEMBL2325079 Bioactive 1-[5-chloro-6-(4-chlorophenyl)-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide
CFAMM00415999 CHEMBL2391140 Bioactive 1-[5-chloro-6-(3-chlorophenyl)-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide
CFAMM00416030 CHEMBL2325076 Bioactive 1-[5-chloro-6-(trifluoromethyl)-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(2-hydroxypropan-2-yl)cyclohexyl]piperidine-4-carboxamide
CFAMM00416023 CHEMBL2315853 Bioactive 1-(5-chloro-1,3-benzoxazol-2-yl)-N-[(1S,2S)-2-phenylmethoxycyclopentyl]piperidine-4-carboxamide
CFAMM00415998 CHEMBL2391142 Bioactive 1-[5-chloro-6-[4-(trifluoromethoxy)phenyl]-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide
CFAMM00416007 CHEMBL2391299 Bioactive 1-[5-chloro-6-(4-fluorophenyl)-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide
CFAMM00416000 CHEMBL2391141 Bioactive 1-[5-chloro-6-(4-ethoxyphenyl)-1,3-benzoxazol-2-yl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]piperidine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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