CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1248
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor AGN-PC-074Z3D family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00321053 Functional Category Bioactive
Superfamily Cruzipain and Beta-lactamase Binder Superfamily
Class Class 2656

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321054 CHEMBL432029 Bioactive AGN-PC-074Z5Y
CFAMM00321053 CHEMBL114837 Bioactive AGN-PC-074Z3D
CFAMM00321052 CHEMBL114547 Bioactive methyl 8-[2-(1,3-dioxoisoindol-2-yl)ethyl]-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00321051 CHEMBL2112550 Bioactive methyl (3S,4S)-8-[3-(1,3-dioxoisoindol-2-yl)propyl]-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00321050 CHEMBL423692 Bioactive methyl 8-[8-(1,3-dioxoisoindol-2-yl)octyl]-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27509 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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