CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12482
Family Name Mitogen-activated protein kinase 14 inhibitor ethyl 2-[[3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carbonyl]amino]acetate family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00416071 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Potassium voltage-gated channel subfamily A member 5 Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Farnesyltransferase beta subunit, putative and Protein farnesy... 6 18
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Poly [ADP-ribose] polymerase 1 Inhibitor 3-morpholin-4-ylmethy... 1 2
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V1a receptor ligand AGN-PC-074VJP family 3 1
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
Vasopressin V1a receptor ligand AGN-PC-074VSA family 3 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Mitogen-activated protein kinase 14 inhibitor ethyl 3-(2,4-dif... 5 1
Mitogen-activated protein kinase 14 inhibitor 3-(3-benzamido-4... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-(2,4-difluoroa... 6 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416071 CHEMBL2316196 Bioactive ethyl 2-[[3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carbonyl]amino]acetate
CFAMM00416074 CHEMBL2316475 Bioactive 3-(2,4-difluoroanilino)-N-(2-methoxyethyl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide
CFAMM00416073 CHEMBL2316199 Bioactive methyl (2S)-2-[[3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carbonyl]amino]-4-methylpentanoate
CFAMM00416072 CHEMBL2316197 Bioactive dimethyl (2S)-2-[[3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carbonyl]amino]pentanedioate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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