CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12483
Family Name Mitogen-activated protein kinase 14 inhibitor ethyl 3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxylate family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00416077 Functional Category Bioactive
Superfamily Retinal dehydrogenase 1 and Cellular tumor antigen p53 Binder Superfamily 3
Class Class 3542

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Retinal dehydrogenase 1 and Menin inhibitor CHEMBL1507858 family 1 6
Mitogen-activated protein kinase 14 inhibitor Skepinone-L family 11 31
Mitogen-activated protein kinase 14 inhibitor N-[2,4-difluoro-... 4 1
Mitogen-activated protein kinase 14 inhibitor ethyl 2-[[3-(2,4... 4 0
Mitogen-activated protein kinase 14 inhibitor 3-(3-benzamido-4... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-(2,4-difluoroa... 6 0
Retinoic acid receptor RXR-beta and Retinoic acid receptor RXR... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416079 CHEMBL2316205 Bioactive 2-hydroxyethyl 3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxylate
CFAMM00416078 CHEMBL2316203 Bioactive propyl 3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxylate
CFAMM00416077 CHEMBL2316202 Bioactive ethyl 3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxylate
CFAMM00416076 CHEMBL2316201 Bioactive methyl 3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxylate
CFAMM00416080 CHEMBL2316206 Bioactive 2-morpholin-4-ylethyl 3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27419 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543