CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12492
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-(cyclohexylmethyl)-6-methoxy-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00416123 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Cytochrome P450 3A4 Binder Superfamily
Class Class 137

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
B1 bradykinin receptor ligand AGN-PC-00CTAF family 1 3
Cannabinoid receptor 1 ligand N-(cyclobutylmethyl)-3-[[4-(meth... 1 1
Cannabinoid receptor 1 and Cytochrome P450 3A4 ligand N-(oxan-... 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-(cy... 1 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 0


External ID

Functional Category

Molecule Name

CFAMM00416126 CHEMBL2316378 Bioactive 6-methoxy-N-(oxan-4-ylmethyl)-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
CFAMM00416124 CHEMBL2316377 Bioactive N-(cyclobutylmethyl)-6-methoxy-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
CFAMM00416123 CHEMBL2316376 Bioactive N-(cyclohexylmethyl)-6-methoxy-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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