CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12496
Family Name Mitogen-activated protein kinase 14 inhibitor 3-(2,4-difluoroanilino)-N-(2-hydroxyethyl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00416132 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Potassium voltage-gated channel subfamily A member 5 Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Mitogen-activated protein kinase 14 inhibitor ethyl 2-[[3-(2,4... 4 0
Mitogen-activated protein kinase 14 inhibitor ethyl 3-(2,4-dif... 5 1
Mitogen-activated protein kinase 14 inhibitor 3-(3-benzamido-4... 2 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 3 0


External ID

Functional Category

Molecule Name

CFAMM00416132 CHEMBL2316478 Bioactive 3-(2,4-difluoroanilino)-N-(2-hydroxyethyl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide
CFAMM00416131 CHEMBL2316480 Bioactive 3-(2,4-difluoroanilino)-N-(1,3-dihydroxypropan-2-yl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide
CFAMM00416130 CHEMBL2316479 Bioactive 3-(2,4-difluoroanilino)-N-(2,3-dihydroxypropyl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide
CFAMM00416135 CHEMBL2316473 Bioactive N-(2-chloroethyl)-3-(2,4-difluoroanilino)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide
CFAMM00416134 CHEMBL2316474 Bioactive 3-(2,4-difluoroanilino)-N-(2-methylsulfanylethyl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide
CFAMM00416133 CHEMBL2316476 Bioactive 3-(2,4-difluoroanilino)-N-(2-methylsulfonylethyl)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulene-9-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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