CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12503
Family Name Coagulation factor X and Prothrombin inhibitor SureCN14502287 family
No. of Seeds 16 No. of Other Members 5
Family Centroid CFAMM00416215 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 13
Class Class 1000

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Rivaroxaban Family 10 18
Atrial natriuretic peptide receptor 1 Ligand Ataciguat Family 7 45
Phospholipase D1 Inhibitor Halopemide Family 17 111
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Thyroid hormone receptor beta and Cellular tumor antigen p53 l... 1 4
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
Coagulation factor X inhibitor AGN-PC-04YPWA family 3 1
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 16 5
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 7 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
Coagulation factor X and Prothrombin inhibitor SureCN6592460 f... 14 1
Coagulation factor X inhibitor SureCN14490781 family 15 0
Coagulation factor X inhibitor SureCN4855529 family 6 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Coagulation factor X inhibitor SureCN5432520 family 6 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 6 1
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Coagulation factor X inhibitor SureCN8257336 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416199 CHEMBL399593 Bioactive SureCN14502194
CFAMM00416206 CHEMBL391527 Bioactive 5-chloro-N-[(1S,2R)-2-[[4-(2-oxopyridin-1-yl)benzoyl]amino]cyclohexyl]thiophene-2-carboxamide
CFAMM00416198 CHEMBL234812 Bioactive AGN-PC-076AAV
CFAMM00416213 CHEMBL232325 Bioactive SureCN14490749
CFAMM00416205 CHEMBL231748 Bioactive AGN-PC-076AAW
CFAMM00416197 CHEMBL401444 Bioactive SureCN14490761
CFAMM00416212 CHEMBL393814 Bioactive AGN-PC-076AAX
CFAMM00416196 CHEMBL233173 Bioactive SureCN14490754
CFAMM00416211 CHEMBL400017 Bioactive SureCN14502107
CFAMM00416218 CHEMBL393521 Bioactive SureCN14490766
CFAMM00416210 CHEMBL232566 Bioactive SureCN5434694
CFAMM00416202 CHEMBL233543 Bioactive SureCN14490767
CFAMM00416217 CHEMBL393421 Bioactive AGN-PC-076AAU
CFAMM00416208 CHEMBL237286 Bioactive SureCN14490760
CFAMM00416201 CHEMBL233542 Bioactive SureCN8306408
CFAMM00416215 CHEMBL233992 Bioactive SureCN14502287

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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