CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12505
Family Name Glucocorticoid receptor and Mineralocorticoid receptor ligand (5Z)-5-[(3-hydroxyphenyl)methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol family
No. of Seeds 22 No. of Other Members 1
Family Centroid CFAMM00299969 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Mineralocorticoid receptor Binder Superfamily 3
Class Class 332

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Glucocorticoid receptor ligand (5Z)-5-[(4-chlorophenyl)methyli... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416252 CHEMBL232375 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[[2-methyl-3-(trifluoromethyl)phenyl]methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416265 CHEMBL234599 Bioactive (5Z)-5-[(2-fluorophenyl)methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416251 CHEMBL232374 Bioactive (5Z)-10-methoxy-5-[(4-methoxyphenyl)methylidene]-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416264 CHEMBL233995 Bioactive (5Z)-5-[[4-fluoro-2-(methoxymethoxymethyl)phenyl]methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416257 CHEMBL232190 Bioactive (5Z)-5-[[4-fluoro-2-(hydroxymethyl)phenyl]methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416270 CHEMBL232760 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(3-methylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416250 CHEMBL401433 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(2-methylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416263 CHEMBL231757 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(2-phenylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416256 CHEMBL391885 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[[4-(trifluoromethoxy)phenyl]methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416269 CHEMBL232761 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416249 CHEMBL231976 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(4-methylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416262 CHEMBL231772 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(3-phenoxyphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416255 CHEMBL232390 Bioactive (5Z)-5-[[4-fluoro-2-[(E)-hydroxyiminomethyl]phenyl]methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416268 CHEMBL232175 Bioactive (5Z)-5-[(4-hydroxyphenyl)methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416261 CHEMBL231770 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(3-phenylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416254 CHEMBL437556 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(4-phenylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416267 CHEMBL232174 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[(4-propan-2-ylphenyl)methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416260 CHEMBL231771 Bioactive (5Z)-10-methoxy-2,2,4-trimethyl-5-[[3-(trifluoromethoxy)phenyl]methylidene]-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416253 CHEMBL232376 Bioactive (5Z)-5-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416266 CHEMBL232173 Bioactive (5Z)-5-[(4-ethylphenyl)methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol
CFAMM00416259 CHEMBL231966 Bioactive (5Z)-5-[[2-(diethylaminomethyl)-4-fluorophenyl]methylidene]-10-methoxy-2,2,4-trimethyl-4a,12a-dihydro-1H-chromeno[3,4-f]quinolin-9-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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