CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1252
Family Name Pol polyprotein inhibitor AHPBA deriv. 33 family
No. of Seeds 13 No. of Other Members 0
Family Centroid CFAMM00321071 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 9
Class Class 323

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Nelfinavir Family 11 26
Plasmepsin-2 Inhibitor KNI-10314 Family 6 2
Pol polyprotein inhibitor AHPBA 33 family 2 6
Pol polyprotein inhibitor AHPBA 25 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00321075 CHEMBL116723 Bioactive AHPBA deriv. 31
CFAMM00321068 CHEMBL117495 Bioactive AHPBA deriv. 38
CFAMM00321076 CHEMBL117024 Bioactive AHPBA deriv. 41
CFAMM00321074 CHEMBL114674 Bioactive AHPBA deriv. 46
CFAMM00321067 CHEMBL115332 Bioactive AHPBA deriv. 34
CFAMM00321073 CHEMBL327147 Bioactive AHPBA deriv. 40
CFAMM00321072 CHEMBL116552 Bioactive AHPBA deriv. 37
CFAMM00321071 CHEMBL117088 Bioactive AHPBA deriv. 33
CFAMM00321079 CHEMBL117769 Bioactive AHPBA deriv. 36
CFAMM00321070 CHEMBL116439 Bioactive AHPBA deriv. 32
CFAMM00321078 CHEMBL325824 Bioactive AHPBA deriv. 35
CFAMM00321069 CHEMBL325199 Bioactive AHPBA deriv. 42
CFAMM00321077 CHEMBL324524 Bioactive AHPBA deriv. 28

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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