CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12522
Family Name Dipeptidyl peptidase 4 inhibitor (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N,N-dimethylpyrrolidine-3-carboxamide family
No. of Seeds 11 No. of Other Members 13
Family Centroid CFAMM00416312 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 Binder Superfamily 8
Class Class 3167

Cousin Family NamesSeedsMembers
Tubulin beta chain Inhibitor Tasidotin Family 1 1
Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Family 9 46
Dipeptidyl peptidase 4 inhibitor SureCN2401277 family 1 13
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 1 3
Dipeptidyl peptidase 4 inhibitor 3-[(3S,5S)-5-[(2S)-2-cyanopyr... 2 3
Dipeptidyl peptidase 4 inhibitor 2-[(3R,5S)-5-[(2S)-2-cyanopyr... 4 2
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S,5S)-5-methyl-4... 2 0
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-(morpholine... 1 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 0
Dipeptidyl peptidase 4 inhibitor SureCN5207366 family 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416327 CHEMBL400613 Bioactive (2S)-1-[(2S,4S)-4-(piperidine-1-carbonyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00416307 CHEMBL234373 Bioactive (2S)-1-[(2S,4S)-4-(azetidine-1-carbonyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00416326 CHEMBL428369 Bioactive (2S)-1-[(2S,4S)-4-(pyrrolidine-1-carbonyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00416312 CHEMBL232103 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N,N-dimethylpyrrolidine-3-carboxamide
CFAMM00416325 CHEMBL400614 Bioactive (2S)-1-[(2S,4S)-4-(azepane-1-carbonyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00416311 CHEMBL232315 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]pyrrolidine-3-carboxamide
CFAMM00416317 CHEMBL391559 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N-methylpyrrolidine-3-carboxamide
CFAMM00416329 CHEMBL393498 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N,N-diethylpyrrolidine-3-carboxamide
CFAMM00416309 CHEMBL232316 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N-ethylpyrrolidine-3-carboxamide
CFAMM00416315 CHEMBL234163 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N-ethyl-N-methylpyrrolidine-3-carboxamide
CFAMM00416321 CHEMBL434960 Bioactive (3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-N-propylpyrrolidine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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