CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12535
Family Name Melanin-concentrating hormone receptor 1 ligand (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-propan-2-ylpyrrolidin-3-yl]pyrrolidine-1-carboxamide family
No. of Seeds 13 No. of Other Members 9
Family Centroid CFAMM00416674 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Dual specificity protein kinase CLK4 Binder Superfamily
Class Class 3712

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 inhibitor N-(3-aminopropyl)-N-[1-(3... 2 22
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00JFT2 ... 8 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00JG7K ... 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416675 CHEMBL394823 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416681 CHEMBL396957 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-(oxan-4-ylmethyl)pyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416674 CHEMBL232257 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-propan-2-ylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416687 CHEMBL389295 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-[(3S)-1-cyclobutylpyrrolidin-3-yl]-N-methylpyrrolidine-1-carboxamide
CFAMM00416680 CHEMBL232619 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-(oxan-4-yl)pyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416686 CHEMBL394560 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-[(3S)-1-(cyclopropylmethyl)pyrrolidin-3-yl]-N-methylpyrrolidine-1-carboxamide
CFAMM00416679 CHEMBL232439 Bioactive (3S)-3-[6-(4-ethylphenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-(oxan-4-yl)pyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416692 CHEMBL232858 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-[(3S)-1-(4,4-dimethylcyclohexyl)pyrrolidin-3-yl]-N-methylpyrrolidine-1-carboxamide
CFAMM00416671 CHEMBL234931 Bioactive (3S)-3-[6-(4-ethylphenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-methylpyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416684 CHEMBL232209 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-(oxolan-3-ylmethyl)pyrrolidin-3-yl]pyrrolidine-1-carboxamide
CFAMM00416670 CHEMBL233889 Bioactive SureCN6411392
CFAMM00416689 CHEMBL232662 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-[(3S)-1-cyclopentylpyrrolidin-3-yl]-N-methylpyrrolidine-1-carboxamide
CFAMM00416682 CHEMBL232823 Bioactive (3S)-3-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3-yl]-N-methyl-N-[(3S)-1-[2-(oxan-4-yl)ethyl]pyrrolidin-3-yl]pyrrolidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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