CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1254
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor (2S)-2-[[2-[[(2S)-2-[[2-[3-[(4-methoxyphenyl)methyl]imidazol-4-yl]acetyl]amino]-3-methylpentyl]-(naphthalen-1-ylmethyl)amino]acetyl]amino]-4-methylsulfanylbutanoic acid family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00321081 Functional Category Bioactive
Superfamily Renin Inhibitor Enalkiren Superfamily
Class Class 1526

Cousin Family NamesSeedsMembers
Eluxadoline family 4 85
Renin Inhibitor Enalkiren Family 56 44
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 8
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7
Putative NP ZINC40310254 Family 74 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321081 CHEMBL114739 Bioactive (2S)-2-[[2-[[(2S)-2-[[2-[3-[(4-methoxyphenyl)methyl]imidazol-4-yl]acetyl]amino]-3-methylpentyl]-(naphthalen-1-ylmethyl)amino]acetyl]amino]-4-methylsulfanylbutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26832 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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