CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12552
Family Name Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-pyridin-3-ylpyridin-2-yl)acetamide family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00416792 Functional Category Bioactive
Superfamily Protein-cysteine N-palmitoyltransferase porcupine and Cyclin-dependent kinase 1 Binder Superfamily
Class Class 64

Cousin Family NamesSeedsMembers
Aurora kinase A Inhibitor ABT-348 Family 20 49
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
5-hydroxytryptamine receptor Ligand Sl65.0472 Family 2 16
Vascular endothelial growth factor receptor 2 Ligand 3-(4-amin... 2 5
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Platelet-activating factor acetylhydrolase inhibitor AGN-PC-01... 15 4
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 5 0
3-phosphoinositide-dependent protein kinase 1 and Serine/threo... 2 2
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-... 4 1
Transient receptor potential cation channel subfamily V member... 1 0
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2


External ID

Functional Category

Molecule Name

CFAMM00416799 CHEMBL2322627 Bioactive 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-thiophen-2-ylpyridin-2-yl)acetamide
CFAMM00416798 CHEMBL2322623 Bioactive 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-pyrimidin-5-ylpyridin-2-yl)acetamide
CFAMM00416796 CHEMBL2322626 Bioactive 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-thiophen-3-ylpyridin-2-yl)acetamide
CFAMM00416792 CHEMBL2323233 Bioactive 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-pyridin-3-ylpyridin-2-yl)acetamide
CFAMM00416791 CHEMBL2323231 Bioactive 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-phenylpyridin-2-yl)acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



59155 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543