CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12553
Family Name Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-[5-(furan-3-yl)pyridin-2-yl]-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00416806 Functional Category Bioactive
Superfamily Beta-lactamase and Cytochrome P450 3A4 Binder Superfamily
Class Class 3402

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Arachidonate 15-lipoxygenase and Nonstructural protein 1 inhib... 1 0


External ID

Functional Category

Molecule Name

CFAMM00416802 CHEMBL2322628 Bioactive N-[5-(furan-3-yl)pyrimidin-2-yl]-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
CFAMM00416801 CHEMBL2322629 Bioactive N-[5-(furan-2-yl)pyrimidin-2-yl]-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
CFAMM00416806 CHEMBL2322624 Bioactive N-[5-(furan-3-yl)pyridin-2-yl]-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
CFAMM00416805 CHEMBL2322625 Bioactive N-[5-(furan-2-yl)pyridin-2-yl]-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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