CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12574
Family Name Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibitor 1'-(6-methoxyquinoline-3-carbonyl)-1-propan-2-ylspiro[4,6-dihydroindazole-5,4'-piperidine]-7-one family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00416906 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Superfamily
Class Class 842

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 5 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 2
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 5-(5-... 10 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 7-met... 2 1
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
B2 bradykinin receptor and Cytochrome P450 3A4 ligand SureCN15... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00416906 CHEMBL2323628 Bioactive 1'-(6-methoxyquinoline-3-carbonyl)-1-propan-2-ylspiro[4,6-dihydroindazole-5,4'-piperidine]-7-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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