CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1260
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor (2R)-N'-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-[[4-(2-methoxyphenyl)phenyl]methyl]butanediamide family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00321186 Functional Category Bioactive
Superfamily Pol polyprotein and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3076

Cousin Family NamesSeedsMembers
Zucapsacin family 7 177
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 11 8
Pol polyprotein inhibitor 180968-31-4 family 8 13
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Pol polyprotein inhibitor (2R,3R,4R,5R)-2,3,4-trihydroxy-N,N'-... 3 3
Pol polyprotein inhibitor MK-944a family 6 1
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor AC1LADII family 12 1
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 3
Pol polyprotein inhibitor L-689,502 family 17 2
A disintegrin and metalloproteinase with thrombospondin motifs... 2 2
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 4
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Pol polyprotein inhibitor AC1NS2O6 family 3 0
Pol polyprotein inhibitor (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopy... 3 0
Neprilysin inhibitor (2S)-4-methoxy-2-[[1-[[(1R,2S)-2-(4-metho... 1 0
Sodium channel protein type 9 subunit alpha ligand (1R,2R)-N-b... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321183 CHEMBL114804 Bioactive (2R)-N'-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-[(4-methoxyphenyl)methyl]butanediamide
CFAMM00321186 CHEMBL9086 Bioactive (2R)-N'-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-[[4-(2-methoxyphenyl)phenyl]methyl]butanediamide
CFAMM00321185 CHEMBL8553 Bioactive (2R)-N'-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-[[4-(3-methoxyphenyl)phenyl]methyl]butanediamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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