CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1263
Family Name Neutrophil elastase inhibitor SureCN7448165 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00321199 Functional Category Bioactive
Superfamily Cellular tumor antigen p53 and Menin Binder Superfamily 2
Class Class 3199

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
72 kDa type IV collagenase Inhibitor SC-74020 Family 1 21
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 2 1
Chymotrypsin-like elastase family member 1 and Neutrophil elas... 1 12
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor KB-74... 2 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrophen... 1 1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 7 11
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 3 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321199 CHEMBL114868 Bioactive SureCN7448165
CFAMM00321198 CHEMBL307315 Bioactive 2-[3-[(4-acetamidophenyl)sulfonylamino]-2-oxo-6-phenylpyridin-1-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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