CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1264
Family Name Disintegrin and metalloproteinase domain-containing protein 17 and Collagenase 3 inhibitor (8S,11R,12S)-12-N-hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00321208 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 Binder Superfamily 4
Class Class 608

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Cathepsin S inhibitor SureCN7062841 family 7 7
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-2-... 6 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 10 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321208 CHEMBL431680 Bioactive (8S,11R,12S)-12-N-hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
CFAMM00321207 CHEMBL325421 Bioactive (8S,11R,12S)-12-N-hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-11-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
CFAMM00321206 CHEMBL115263 Bioactive (8S,11R,12S)-8-N-(2-amino-2-oxoethyl)-12-N-hydroxy-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
CFAMM00321205 CHEMBL432990 Bioactive (8S,11R,12S)-11-[[4-(2,6-difluorophenyl)phenyl]methyl]-12-N-hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
CFAMM00321211 CHEMBL323929 Bioactive (8S,11R,12S)-12-N-hydroxy-8-N-[2-(methylamino)-2-oxoethyl]-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
CFAMM00321204 CHEMBL325163 Bioactive (8S,11R,12S)-12-N-hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
CFAMM00321209 CHEMBL114878 Bioactive (8S,11R,12S)-11-[[4-[3,5-bis(trifluoromethyl)phenyl]phenyl]methyl]-12-N-hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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