CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1265
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN7524408 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00321213 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Amine oxidase [flavin-containing] B Binder Superfamily
Class Class 1027

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
Toll-like receptor 7 Ligand GS-9620 Family 2 4
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-t... 1 2
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Adenosine receptor A1 ligand 8-(2-amino-4-nitrophenyl)-1,3-dim... 1 0
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKE family 3 5
Histamine H4 receptor ligand SureCN602132 family 1 8
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 5
Adenosine receptor A3 and Adenosine receptor A1 ligand (8R)-8-... 4 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Adenosine receptor A3 ligand 3-(cyclopropylmethyl)-8-methoxy-1... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 1 0
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 2
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Adenosine receptor A1 ligand 3-(4-Aminophenethyl)-8-(3-noradam... 1 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321213 CHEMBL325948 Bioactive SureCN7524408
CFAMM00321212 CHEMBL114886 Bioactive 5-oxo-5-[3-[(E)-2-(1,3,7-trimethyl-2,6-dioxopurin-8-yl)ethenyl]anilino]pentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27043 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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