CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12661
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4-(diethylamino)phenyl]methyl]-4-methyl-N-(4-methylphenyl)benzenesulfonamide family
No. of Seeds 7 No. of Other Members 11
Family Centroid CFAMM00328248 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 16
Class Class 151

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Cannabinoid receptor 1 Ligand AVE1625 Family 2 19
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
5-hydroxytryptamine receptor 2A Ligand Fananserin Family 13 49
Carbonic anhydrase 2 Inhibitor Dansylamide Family 1 9
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 3 Ligand CP... 4 26
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
D(2) dopamine receptor Ligand 1-benzyl-4-[3-(methylsulfonyl)ph... 2 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 10
Sodium-dependent noradrenaline transporter inhibitor 3-[1-(2-f... 2 13
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 9 26
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 10
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-chl... 2 16
5-hydroxytryptamine receptor 2A ligand AGN-PC-075LXD family 4 4
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 6 8
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 4
Mu-type opioid receptor and Mu-type opioid receptor ligand N-[... 2 4
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 6 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(4-... 2 10
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor (E)-2... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
Growth hormone secretagogue receptor type 1 ligand SureCN48016... 5 4
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor aryls... 2 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 7 0
Prostaglandin G/H synthase 2 inhibitor SureCN6721692 family 4 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Neutrophil collagenase and Stromelysin-1 inhibitor [(1R)-2-met... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 4 1
Orexin receptor type 2 ligand SureCN1039013 family 1 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-014RDG family 1 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 14
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 0
Prothrombin and Proteinase-activated receptor 1 ligand (2S)-N-... 2 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Chymase and Chymotrypsinogen A inhibitor SureCN7836048 family 2 0
C-C chemokine receptor type 5 ligand AC1MHPAZ family 1 0
Glucocorticoid receptor ligand AGN-PC-01X8EB family 1 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00417577 CHEMBL595990 Bioactive n,n'-1,2-phenylenebis(n,4-dimethylbenzenesulfonamide)
CFAMM00417567 CHEMBL2326300 Bioactive N-[[4-(diethylamino)phenyl]methyl]-N-(4-methylphenyl)-4-propan-2-ylbenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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