CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12680
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8358729 family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00417684 Functional Category Bioactive
Superfamily Beta-lactamase and Retinal dehydrogenase 1 Binder Superfamily 20
Class Class 253

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Adenosine receptor A2a Ligand KW-6002 Family 18 195
GP-531 family 1 33
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Prelamin-A/C inhibitor CHEMBL1501476 family 1 2
Survival motor neuron protein and Microtubule-associated prote... 2 14
C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S... 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 13 2
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
Sodium- and chloride-dependent glycine transporter 1 and Potas... 14 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methy... 1 0


External ID

Functional Category

Molecule Name

CFAMM00417680 CHEMBL282114 Bioactive SureCN8360097
CFAMM00417679 CHEMBL325323 Bioactive SureCN8258178
CFAMM00417685 CHEMBL279903 Bioactive SureCN8360099
CFAMM00417678 CHEMBL283242 Bioactive CHEMBL283242
CFAMM00417684 CHEMBL26775 Bioactive SureCN8358729
CFAMM00417677 CHEMBL441223 Bioactive CHEMBL441223
CFAMM00417683 CHEMBL280578 Bioactive CHEMBL280578
CFAMM00417686 CHEMBL432657 Bioactive CHEMBL432657
CFAMM00417682 CHEMBL286723 Bioactive CHEMBL286723
CFAMM00417681 CHEMBL23308 Bioactive SureCN8358715

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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