CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12698
Family Name Cytochrome P450 3A4 and Peroxisome proliferator-activated receptor gamma ligand 2,4-dichloro-N-[3,5-dichloro-4-(5-methylpyridin-3-yl)oxyphenyl]benzenesulfonamide family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00417766 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 Superfamily
Class Class 2393

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand INT131... 1 3
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 11
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 1 6
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 5 14
Peroxisome proliferator-activated receptor gamma ligand N-[3-a... 1 4


External ID

Functional Category

Molecule Name

CFAMM00417766 CHEMBL2338480 Bioactive 2,4-dichloro-N-[3,5-dichloro-4-(5-methylpyridin-3-yl)oxyphenyl]benzenesulfonamide
CFAMM00417759 CHEMBL2338479 Bioactive 2,4-dichloro-N-[3,5-dichloro-4-(5-cyanopyridin-3-yl)oxyphenyl]benzenesulfonamide
CFAMM00417757 CHEMBL2331772 Bioactive 2,4-dichloro-N-[3,5-dichloro-4-(5-chloropyridin-3-yl)oxyphenyl]benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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