CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12705
Family Name Rho-associated protein kinase 2 inhibitor 1-(3-hydroxy-1-phenylpropyl)-3-[4-(1H-pyrazol-4-yl)phenyl]urea family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00417814 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 and Rho-associated protein kinase 2 Binder Superfamily
Class Class 1301

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 12 108
Pol polyprotein inhibitor AC1L9T0J family 4 1
Pol polyprotein inhibitor SE063 family 22 1
Transient receptor potential cation channel subfamily V member... 7 17
Pol polyprotein inhibitor AC1LATY6 family 27 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 5 11
Rho-associated protein kinase 2 inhibitor 1-ethyl-1-[(3-methox... 15 8
Rho-associated protein kinase 2 inhibitor benzyl N-[4-(1H-pyra... 1 0
Pol polyprotein inhibitor AC1LAMOI family 12 0
Pol polyprotein inhibitor AC1LAIVI family 4 0
Pol polyprotein inhibitor AC1LALDH family 6 0
Cell division cycle 7-related protein kinase and Dual specific... 3 0
Pol polyprotein inhibitor AC1LAIVF family 2 1


External ID

Functional Category

Molecule Name

CFAMM00417815 CHEMBL2332056 Bioactive 1-[1-(3-fluorophenyl)-3-hydroxypropyl]-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417814 CHEMBL2332057 Bioactive 1-(3-hydroxy-1-phenylpropyl)-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417813 CHEMBL2332058 Bioactive 1-(2-hydroxy-1-phenylethyl)-3-[4-(1H-pyrazol-4-yl)phenyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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