CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12706
Family Name Rho-associated protein kinase 2 inhibitor 1-ethyl-1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]urea family
No. of Seeds 15 No. of Other Members 8
Family Centroid CFAMM00417839 Functional Category Bioactive
Superfamily Beta-secretase 1 and C-C chemokine receptor type 3 Binder Superfamily
Class Class 4364

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
D(2) dopamine receptor and D(3) dopamine receptor Ligand Benzy... 2 9
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 50 36
Transient receptor potential cation channel subfamily V member... 7 17
Transient receptor potential cation channel subfamily V member... 2 1
Rho-associated protein kinase 2 inhibitor SureCN1253489 family 11 28
Rho-associated protein kinase 2 inhibitor SureCN1253789 family 1 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 6 2
Rho-associated protein kinase 2 inhibitor 1-(3-hydroxy-1-pheny... 3 3
Rho-associated protein kinase 2 inhibitor SureCN1988546 family 21 2
Rho-associated protein kinase 2 inhibitor SureCN12561814 family 4 0
Rho-associated protein kinase 2 and RAC-alpha serine/threonine... 3 0
Cell division cycle 7-related protein kinase inhibitor SureCN4... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00417839 CHEMBL2332098 Bioactive 1-ethyl-1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417817 CHEMBL2332070 Bioactive 1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]-1-(3-pyrrolidin-1-ylpropyl)urea
CFAMM00417832 CHEMBL2332069 Bioactive 1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]-1-(2-pyrrolidin-1-ylethyl)urea
CFAMM00417824 CHEMBL2332060 Bioactive 1-ethyl-1-[(3-methoxyphenyl)methyl]-3-[2-[(3S)-1-methylpyrrolidin-3-yl]oxy-4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417838 CHEMBL2332099 Bioactive 1-cyclopropyl-1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417831 CHEMBL2332068 Bioactive 1-[2-(dimethylamino)ethyl]-1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417837 CHEMBL2332097 Bioactive 1-[(3-methoxyphenyl)methyl]-1-methyl-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417829 CHEMBL2332065 Bioactive 1-(2-hydroxyethyl)-1-[(3-methoxyphenyl)methyl]-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417828 CHEMBL2332064 Bioactive 1-[(3-methoxyphenyl)methyl]-1-propan-2-yl-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417827 CHEMBL2332067 Bioactive SureCN3246122
CFAMM00417819 CHEMBL2332074 Bioactive 1-[(3-methoxyphenyl)methyl]-1-(3-piperidin-1-ylpropyl)-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417818 CHEMBL2332072 Bioactive 1-[(3-methoxyphenyl)methyl]-1-(3-morpholin-4-ylpropyl)-3-[4-(1H-pyrazol-4-yl)phenyl]urea
CFAMM00417825 CHEMBL2332061 Bioactive SureCN3242868

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45422 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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