CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1272
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-benzodioxol-5-yl)-3-[[2-[(3S)-2-oxo-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]acetyl]amino]propanoic acid family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00321283 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 4
Class Class 851

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 23 8
Endothelin-1 receptor and Endothelin B receptor ligand SureCN1... 3 16
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 8 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6223678 f... 14 1
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X2R ... 1 3
Somatostatin receptor type 3 ligand AGN-PC-07Z9ZZ family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321279 CHEMBL315015 Bioactive SureCN6421322
CFAMM00321284 CHEMBL51391 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-3-[[2-[6-cyclopropyl-2-oxo-3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-ylmethylamino)pyrazin-1-yl]acetyl]amino]propanoic acid
CFAMM00321277 CHEMBL115130 Bioactive (3S)-3-(2,2-difluoro-1,3-benzodioxol-5-yl)-3-[[2-[(3S)-2-oxo-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]acetyl]amino]propanoic acid
CFAMM00321283 CHEMBL326724 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-3-[[2-[(3S)-2-oxo-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]pyrrolidin-1-yl]acetyl]amino]propanoic acid
CFAMM00321276 CHEMBL364562 Bioactive SureCN2906389
CFAMM00321275 CHEMBL184369 Bioactive SureCN2906029

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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