CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12722
Family Name C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-fluorophenyl]acetamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00417928 Functional Category Bioactive
Superfamily C-C chemokine receptor type 1 and Transient receptor potential cation channel subfamily M member 8 Binder Superfamily
Class Class 217

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Renin Inhibitor Ro-66-1168 Family 10 30
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
D(4) dopamine receptor ligand AGN-PC-004XJQ family 2 1
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 5 0
C-C chemokine receptor type 1 ligand N-[2-[(2S)-2-amino-3-(5-f... 3 0
Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl... 1 0
Progesterone receptor ligand CHEMBL252850 family 2 0
Progesterone receptor ligand CHEMBL253735 family 2 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 8 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 9 0
Muscarinic acetylcholine receptor M1 and Microtubule-associate... 1 0
P2X purinoceptor 7 inhibitor SureCN3722920 family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00417929 CHEMBL2332932 Bioactive N-[2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]phenyl]acetamide
CFAMM00417928 CHEMBL2332931 Bioactive N-[2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-fluorophenyl]acetamide
CFAMM00417927 CHEMBL2332934 Bioactive N-[2-[(2S)-3-(5-fluorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]phenyl]acetamide
CFAMM00417930 CHEMBL2332933 Bioactive N-[4-fluoro-2-[(2S)-3-(5-fluorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]phenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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