CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12728
Family Name Leucine-rich repeat serine/threonine-protein kinase 2 inhibitor 4-[[(2R)-butan-2-yl]amino]-7-(4-methylsulfonylphenyl)cinnoline-3-carboxamide family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00417960 Functional Category Bioactive
Superfamily Leucine-rich repeat serine/threonine-protein kinase 2 and Orexin receptor type 1 Binder Superfamily
Class Class 208

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-(3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00417961 CHEMBL2333128 Bioactive 4-[[(1R)-1-cyclopropylethyl]amino]-7-(4-methylsulfonylphenyl)cinnoline-3-carboxamide
CFAMM00417960 CHEMBL2333127 Bioactive 4-[[(2R)-butan-2-yl]amino]-7-(4-methylsulfonylphenyl)cinnoline-3-carboxamide
CFAMM00417962 CHEMBL2333129 Bioactive 4-(cyclobutylamino)-7-(4-methylsulfonylphenyl)cinnoline-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27627 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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