CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12746
Family Name Sodium-dependent serotonin transporter and Substance-P receptor ligand 2-chloro-6-[(4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00418020 Functional Category Bioactive
Superfamily Substance-P receptor and Sodium-dependent serotonin transporter Binder Superfamily
Class Class 4934

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxylamine Family 2 91
Histamine H1 receptor Ligand Bepotastine Family 2 2
Substance-P receptor ligand 1-[4-[[3,5-bis(trifluoromethyl)phe... 3 0
Lysosomal Pro-X carboxypeptidase inhibitor 5-(4-chloropyridin-... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 15
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Substance-P receptor and Sodium-dependent serotonin transporte... 11 6
Substance-P receptor and Sodium-dependent serotonin transporte... 11 4
Sodium-dependent serotonin transporter and Substance-P recepto... 1 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 3 9


External ID

Functional Category

Molecule Name

CFAMM00418029 CHEMBL2333614 Bioactive 2-[[4-(3-chlorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-cyclopropyl-4-(trifluoromethyl)pyridine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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