CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12747
Family Name Substance-P receptor and Sodium-dependent serotonin transporter ligand N,N-diethyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-amine family
No. of Seeds 11 No. of Other Members 4
Family Centroid CFAMM00418037 Functional Category Bioactive
Superfamily Substance-P receptor and Nitric oxide synthase, brain Binder Superfamily
Class Class 2845

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxylamine Family 2 91
Substance-P receptor ligand 1-[4-[[3,5-bis(trifluoromethyl)phe... 3 0
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Serine/threonine-protein kinase mTOR inhibitor SureCN2707225 f... 29 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 15
Growth hormone secretagogue receptor type 1 ligand SureCN63605... 5 7
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0074... 2 3
Substance-P receptor and Sodium-dependent serotonin transporte... 11 6
Sodium-dependent serotonin transporter and Substance-P recepto... 4 1
Sodium-dependent serotonin transporter and Substance-P recepto... 1 0
Nitric oxide synthase, inducible inhibitor SureCN2258300 family 2 24
Nociceptin receptor and Potassium voltage-gated channel subfam... 3 9
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418033 CHEMBL2333624 Bioactive 2-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-6-pyrrolidin-1-yl-4-(trifluoromethyl)pyridine
CFAMM00418032 CHEMBL2333625 Bioactive 2-[6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-yl]-2-azabicyclo[3.1.0]hexane
CFAMM00418031 CHEMBL2333626 Bioactive 2-(2,5-dihydropyrrol-1-yl)-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine
CFAMM00418037 CHEMBL2333618 Bioactive N,N-diethyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-amine
CFAMM00418030 CHEMBL2333621 Bioactive N-ethyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-N-methyl-4-(trifluoromethyl)pyridin-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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