CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12767
Family Name Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-[1-(quinoxaline-2-carbonyl)piperidin-4-yl]acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00418135 Functional Category Bioactive
Superfamily Prelamin-A/C and Integrin beta-3 Binder Superfamily 2
Class Class 1390

Cousin Family NamesSeedsMembers
26S proteasome Inhibitor Bortezomib Family 7 65
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Cathepsin S inhibitor N-[(S)-[1-(1-cyanocyclopropyl)triazol-4-... 5 12
Cathepsin S inhibitor N-[(S)-[1-(1-cyanocyclopropyl)triazol-4-... 1 0
Cathepsin S inhibitor 4-acetamido-N-[(S)-[1-(1-cyanocyclopropy... 4 0
Cannabinoid receptor 1 and Cytochrome P450 3A4 ligand N-(oxan-... 2 0
Neutrophil elastase inhibitor N-[(2S)-3-methyl-1-oxo-1-[(2S)-2... 4 4
Macrophage colony-stimulating factor 1 receptor and Mast/stem ... 4 0
Dipeptidyl peptidase 4 inhibitor SureCN5777667 family 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00418135 CHEMBL2334699 Bioactive (1S,3S,5S)-2-[(2S)-2-amino-2-[1-(quinoxaline-2-carbonyl)piperidin-4-yl]acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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