CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1277
Family Name Sodium-dependent dopamine transporter and Muscarinic acetylcholine receptor M1 ligand N-[2-[3-[bis(4-fluorophenyl)methoxy]-8-azabicyclo[3.2.1]octan-8-yl]ethyl]benzamide family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00321313 Functional Category Bioactive
Superfamily Plasmepsin-2 and Plasmepsin-1 Binder Superfamily
Class Class 923

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Substance-P receptor Ligand SCH-388714 Family 26 8
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(4-me... 2 9
Substance-P receptor ligand (1S,2R)-2-[(1R)-1-[3,5-bis(trifluo... 12 0
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 0
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Beta-secretase 1 and Cathepsin E inhibitor 1-N-[(1R,2S)-3-(3,5... 3 8
Plasmepsin-1 and Plasmepsin-2 inhibitor N-[(2S,3S)-5-[[(2S)-1-... 2 4
Beta-lactamase inhibitor CHEMBL1326254 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321313 CHEMBL115253 Bioactive N-[2-[3-[bis(4-fluorophenyl)methoxy]-8-azabicyclo[3.2.1]octan-8-yl]ethyl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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