CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1278
Family Name Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OX family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00321316 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M2 Binder Superfamily 2
Class Class 511

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-349821 Family 49 228
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 13
Muscarinic acetylcholine receptor M2 ligand (2-chlorophenyl)-[... 7 3
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ITY family 16 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ZZ3 family 11 1
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 9 4
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 4 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 0
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04X9O... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074P5J family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321316 CHEMBL11527 Bioactive AGN-PC-0745OX
CFAMM00321315 CHEMBL418530 Bioactive AGN-PC-0745NU

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27028 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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