CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12798
Family Name Macrophage metalloelastase inhibitor 2-(2,5-dichlorophenyl)sulfonyl-N-hydroxy-6-phenoxy-3,4-dihydro-1H-isoquinoline-1-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00418338 Functional Category Bioactive
Superfamily Stromelysin-1 and Neutrophil collagenase Binder Superfamily 3
Class Class 4031

Cousin Family NamesSeedsMembers
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Growth hormone secretagogue receptor type 1 ligand 2-benzylsul... 2 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8


External ID

Functional Category

Molecule Name

CFAMM00418338 CHEMBL2337131 Bioactive 2-(2,5-dichlorophenyl)sulfonyl-N-hydroxy-6-phenoxy-3,4-dihydro-1H-isoquinoline-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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