CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1281
Family Name Corticotropin-releasing factor receptor 1 ligand N-(cyclopropylmethyl)-8-(2,4-dichlorophenyl)-2-methyl-N-propylquinolin-4-amine family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00321330 Functional Category Bioactive
Superfamily Nociceptin receptor and Mu-type opioid receptor Binder Superfamily 4
Class Class 471

Cousin Family NamesSeedsMembers
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Sarcoplasmic/endoplasmic reticulum calcium ATPase inhibitor qu... 2 60
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 43 17
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Metabotropic glutamate receptor 5 Ligand 3-fluoro-5-(2-methylq... 3 2
Metabotropic glutamate receptor 5 Ligand 3-chloro-5-(2-methylq... 3 4
Metabotropic glutamate receptor 5 Ligand 7-m-tolyl-1,6-naphthy... 4 2
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YYL... 1 3
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 6-(2-... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)... 1 0
Corticotropin-releasing factor receptor 1 ligand 2-(2,4-dichlo... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00321330 CHEMBL115389 Bioactive N-(cyclopropylmethyl)-8-(2,4-dichlorophenyl)-2-methyl-N-propylquinolin-4-amine
CFAMM00321329 CHEMBL325430 Bioactive AGN-PC-074YR3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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